Biologically Active Small Molecules

A lipophilic derivative of ferulic acid, with increased ability to cross cell membranes less DPPH radical scavenging capacity than ferulic acid (IC50 = 66.7 &muM for FAEE vs.

A lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes at 10-25 &microg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces NO generation from LPS-stimulated

A lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes at 10-25 &microg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces NO generation from LPS-stimulated

A lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes at 10-25 &microg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces NO generation from LPS-stimulated

A plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for ER&alpha (IC₅₀ = 33.1 nM) and an agonist/antagonist for ER&beta (IC₅₀ = 180.

A plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for ER&alpha (IC₅₀ = 33.1 nM) and an agonist/antagonist for ER&beta (IC₅₀ = 180.

A plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for ER&alpha (IC₅₀ = 33.1 nM) and an agonist/antagonist for ER&beta (IC₅₀ = 180.

FeTMPyP is a synthetic porphyrin complexed with iron, which acts as a peroxynitrite decomposition catalyst. The rate constant for decomposition of peroxynitrite by FeTMPyP is 2.

FeTMPyP is a synthetic porphyrin complexed with iron, which acts as a peroxynitrite decomposition catalyst. The rate constant for decomposition of peroxynitrite by FeTMPyP is 2.

FeTMPyP is a synthetic porphyrin complexed with iron, which acts as a peroxynitrite decomposition catalyst. The rate constant for decomposition of peroxynitrite by FeTMPyP is 2.

FeTMPyP is a synthetic porphyrin complexed with iron, which acts as a peroxynitrite decomposition catalyst. The rate constant for decomposition of peroxynitrite by FeTMPyP is 2.

A ferric porphyrin complex that causes the decomposition of peroxynitrite by catalytic isomerization to produce nitrate both in vitro and in vivo, resulting in cytoprotection (EC₅₀ = 5 &microM).