Biologically Active Small Molecules

An indoleacetamide that acts as a high affinity TSPO agonist (Ki = 5 nM) enhances steroidogenesis of neuroactive steroids, thus potentiating GABAA receptor signaling to produce anticonvulsant, anxiolytic, and sedative activity in both animal and

An indoleacetamide that acts as a high affinity TSPO agonist (Ki = 5 nM) enhances steroidogenesis of neuroactive steroids, thus potentiating GABAA receptor signaling to produce anticonvulsant, anxiolytic, and sedative activity in both animal and

An indoleacetamide that acts as a high affinity TSPO agonist (Ki = 5 nM) enhances steroidogenesis of neuroactive steroids, thus potentiating GABAA receptor signaling to produce anticonvulsant, anxiolytic, and sedative activity in both animal and

An indoleacetamide that acts as a high affinity TSPO agonist (Ki = 5 nM) enhances steroidogenesis of neuroactive steroids, thus potentiating GABAA receptor signaling to produce anticonvulsant, anxiolytic, and sedative activity in both animal and

An inhibitor of &beta-catenin/Tcf-mediated transcription and an antagonist of ligand-dependent activation of PPAR&gamma and PPAR&delta blocks the recruitment of &beta-catenin and GRIP1 to PPAR&gamma and PPAR&delta selectively toxic to some

An inhibitor of &beta-catenin/Tcf-mediated transcription and an antagonist of ligand-dependent activation of PPAR&gamma and PPAR&delta blocks the recruitment of &beta-catenin and GRIP1 to PPAR&gamma and PPAR&delta selectively toxic to some

An inhibitor of &beta-catenin/Tcf-mediated transcription and an antagonist of ligand-dependent activation of PPAR&gamma and PPAR&delta blocks the recruitment of &beta-catenin and GRIP1 to PPAR&gamma and PPAR&delta selectively toxic to some

An inhibitor of &beta-catenin/Tcf-mediated transcription and an antagonist of ligand-dependent activation of PPAR&gamma and PPAR&delta blocks the recruitment of &beta-catenin and GRIP1 to PPAR&gamma and PPAR&delta selectively toxic to some

A nucleoside analog with antiviral activity, inhibiting thymidine kinases from herpes simplex virus types 1 and 2 with Ki values of 0.14 and 0.95 &microM, while blocking green monkey Vero cell thymidine kinase less effectively (Ki = 53 &microM).

A nucleoside analog with antiviral activity, inhibiting thymidine kinases from herpes simplex virus types 1 and 2 with Ki values of 0.14 and 0.95 &microM, while blocking green monkey Vero cell thymidine kinase less effectively (Ki = 53 &microM).

A nucleoside analog with antiviral activity, inhibiting thymidine kinases from herpes simplex virus types 1 and 2 with Ki values of 0.14 and 0.95 &microM, while blocking green monkey Vero cell thymidine kinase less effectively (Ki = 53 &microM).

A nucleoside analog with antiviral activity, inhibiting thymidine kinases from herpes simplex virus types 1 and 2 with Ki values of 0.14 and 0.95 &microM, while blocking green monkey Vero cell thymidine kinase less effectively (Ki = 53 &microM).