Biologically Active Small Molecules

A derivative of halopemide which potently inhibits both PLD1 (IC₅₀ = 25 nM) and PLD2 (IC₅₀ = 20 nM) prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis.

A derivative of halopemide which potently inhibits both PLD1 (IC₅₀ = 25 nM) and PLD2 (IC₅₀ = 20 nM) prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis.

A derivative of halopemide which potently inhibits both PLD1 (IC₅₀ = 25 nM) and PLD2 (IC₅₀ = 20 nM) prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis.

A natural flavonol and potent antioxidant with anti-inflammatory actions activator of sirtuin 1, inhibitor of the spleen tyrosine kinase SYK, and suppressor of CD36 gene expression.

A natural flavonol and potent antioxidant with anti-inflammatory actions activator of sirtuin 1, inhibitor of the spleen tyrosine kinase SYK, and suppressor of CD36 gene expression.

A natural flavonol and potent antioxidant with anti-inflammatory actions activator of sirtuin 1, inhibitor of the spleen tyrosine kinase SYK, and suppressor of CD36 gene expression.

FK3311 is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (NSAID). FK3311 inhibits LPS-induced thromboxane B₂ (TxB₂ Item No.

FK3311 is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (NSAID). FK3311 inhibits LPS-induced thromboxane B₂ (TxB₂ Item No.

FK3311 is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (NSAID). FK3311 inhibits LPS-induced thromboxane B₂ (TxB₂ Item No.

FK3311 is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (NSAID). FK3311 inhibits LPS-induced thromboxane B₂ (TxB₂ Item No.

FK-409 is a NO donor. It liberates NO in a time-dependent manner with a half-life of approximately 40 minutes in phosphate buffer (pH 7.4) at 37&degC. The IC₅₀ for the inhibition of platelet aggregation is 4.9 &microM.

FK-409 is a NO donor. It liberates NO in a time-dependent manner with a half-life of approximately 40 minutes in phosphate buffer (pH 7.4) at 37&degC. The IC₅₀ for the inhibition of platelet aggregation is 4.9 &microM.