-
M00570
CHO-K1/mouse CTLA4 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses. CTLA4 is constitutively expressed -
M00647
CHO-K1/mouse HVEM Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77HVEM is found on the surface of various cell types, including hematopoietic and non-hematopoietic cells, and is expressed mainly in spleen, thymus, bone marrow, lung and intestines. It has been identified as a canonical TNF receptor, signaling -
M00567
CHO-K1/mouse PD-L1 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. The formation of PD-1 receptor / PD-L1 or B7. -
M00633
CHO-K1/Mouse VISTA Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77V-domain Ig suppressor of T cell activation (VISTA) is a potent negative regulator of T-cell function that is expressed on hematopoietic cells. VISTA levels are heightened within the tumor microenvironment, in which its blockade can enhance -
M00425
CHO-K1/MRGPRX2 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77MRGX2 is a Gq- and Gi-coupled GPCR that binds to several peptides, including the neuropeptide cortistatin-14 and the proadrenomedullin N-terminal peptide (PAMP). It is probably involved in the function of nociceptive neurons and regulation of -
M00424
CHO-K1/MT1/Ga15 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77Melatonin binds to two specific G-protein coupled receptors (GPCR), MT1 (MTNR1A/MEL1A) and MT2 (MTNR1B/MEL1B). MT1 receptors signal via inhibitory G proteins (Ga<sub>i</sub> and Ga<sub>o</sub>) leading to adenylate cyclase inhibition and possibly -
M00312
CHO-K1/MT2/Ga15 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77Melatonin is a neurohormone that plays a key role in the synchronisation of circadian and seasonal functions with cyclic environmental variations. In mammals, two melatonin receptors, MT1 and MT2, have been cloned. -
M00347
CHO-K1/MTLR/Ga15 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77The motilin receptor (MTLR) represents a clinically useful pharmacological target, as agonists binding to the MTLR have gastroprokinetic properties. Motilin is a 22 amino acid peptide that potently stimulates gastrointestinal contractility. -
M00428
CHO-K1/NIACR1/Ga15 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77GPR109A is a high affinity receptor for nicotinic acid (niacin) and is a member of the nicotinic acid receptor family of G protein-coupled receptors (the other identified member being GPR109B). GPR109A is a G<sub>i/o</sub> protein-coupled receptor -
M00199
CHO-K1/NK1 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77Tachykinins are peptides sharing the common C-terminal amino acid sequence Phe-X-Gly-Leu-Met-NH<sub>2</sub>. This neuropeptide family is composed of substance P, neurokinin A, and neurokinin B, which are widely distributed in mammalian central and -
M00200
CHO-K1/NK2 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77Tachykinins are peptides sharing a common C-terminal amino acid sequence: Phe-X-Gly-Leu-Met-NH<sub>2</sub>. This neuropeptide family is composed of substance P, neurokinin A, and neurokinin B, which are widely distributed in mammalian central and -
M00201
CHO-K1/NK3 Stable Cell Line,2vials
Price: $14,010.99List Price: $15,567.77Tachykinins are peptides sharing a common C-terminal amino acid sequence: Phe-X-Gly-Leu-Met-NH<sub>2</sub>. This neuropeptide family is composed of substance P, neurokinin A, and neurokinin B, which are widely distributed in mammalian central and