Viral Gene Delivery

Hepatic Leukemia Factor (HLF) is a member of the proline and acidic-rich (PAR) family, a subset of the bZIP transcription factors. Chromosomal translocation of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemia.

Hepatic Leukemia Factor (HLF) is a member of the proline and acidic-rich (PAR) family, a subset of the bZIP transcription factors. Chromosomal translocation of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemia.

Krueppel-like factor 4 (KLF4) is a zinc finger transcriptional regulator that has been identified as a good indicator of stem cell-like capacity and is subsequently used in iPS cell generation. KFL4 plays an important role in maintaining stem cells,

Krueppel-like factor 4 (KLF4) is a zinc finger transcriptional regulator that has been identified as a good indicator of stem cell-like capacity and is subsequently used in iPS cell generation. KFL4 plays an important role in maintaining stem cells,

LIN28 is a microRNA-binding protein that has been shown to bind the let-7 pre-microRNA and block production of mature let-7 in embryonic stem cells. This activity appears to preserve undifferentiated state of stem cells.

LIN28 is a microRNA-binding protein that has been shown to bind the let-7 pre-microRNA and block production of mature let-7 in embryonic stem cells. This activity appears to preserve undifferentiated state of stem cells.

It has been observed that microRNA (mRNA) miR-211 plays a role in the regulation of cancer metastasis. This lentivirus expresses miR-211 under the control of the EF1A promoter.

It has been observed that microRNA (mRNA) miR-211 plays a role in the regulation of cancer metastasis. This lentivirus expresses miR-211 under the control of the EF1A promoter.

NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture.

NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture.

NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture.

NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture.