(-)-Latifolin, a flavonoid, induces apoptotic cell death by targeting PI3K/AKT/mTOR/p70S6K signaling. (-)-Latifolin significantly inhibits the cell proliferation of oral squamous cell carcinoma (OSCC), and causes the anti-metastatic activities by effectively blocking cell migration, invasion, and adhesion via the inactivation of FAK/Src. (-)-Latifolin suppresses autophagic -related proteins and autophagosome formation. (-)-Latifolin inhibits necroptosis by dephosphorylating necroptosis-regulatory proteins (RIP1, RIP3, and MLKL). (-)-Latifolin has beneficial effects on anti-aging , anti-carcinogenic, anti-inflammatory, and cardio-protective activities .
PubChem CID: 340211
Isomeric SMILES: COC1=CC(=C(C=C1[C@H](C=C)C2=CC=CC=C2O)O)OC
- UPC:
- 51432305
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L996338-1mg
- Product Size:
- 1mg
- CAS:
- 10154-42-4
