LCL521 dihydrochloride is an acid ceramidase ( ACDase ) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase ( ASMase )In VitroLCL521 (1 µM) acts as a potent inhibitor of cellular ACDase activity, whereas 10 µM LCL521 has an additional, decreased affect on the α-form of this enzyme. LCL521 (10µM) causes a time-dependent (1 hours and 5 hours) decrease of the α-ACDase form in MCF7 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:ACDase, ASMase. Specification: 0.98 Molecular Formula: C31H54Cl2N4O7 Molecular Weight: 665.69 PubChem CID: 132585217 Isomeric SMILES: CCCCCCCCCCCCCC(=O)N[C@H](COC(=O)CN(C)C)[C@@H](C1=CC=C(C=C1)[N+](=O)[O-])OC(=O)CN(C)C.Cl.Cl
- UPC:
- 12352107
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L650592-10mg
- CAS:
- 1226759-47-2
- Product Size:
- 10mg
