ligands acting on targets

(R)-(+)-Verapamil Hydrochloride inhibits p-glycoprotein efflux pump in multidrug resistant tumor cells.

(R)-(+)-WIN 55,212-2 mesylate salt.

(R)-(-)-1-Methoxy-2-propylamine.

(R)-(-)-1-Methoxy-2-propylamine.

(R)-(-)-1-Methoxy-2-propylamine.

(R)-(-)-1-Methoxy-2-propylamine.

Product Describtion:(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM,

Product Describtion:(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM,

Product Describtion:(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM,

Product Describtion:(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM,

Information(R)-(-)-Gossypol (AT-101) acetic acid, the R-(-) enantiomer of Gossypol acetic acid, binds withBcl-2,Bcl-xLandMcl-1withKiof 0.32 μM, 0.48 μM and 0.18 μM in cell-free assays: does not inhibit BIR3 domain and BID. AT-101 simultaneously

(R)-Ibuprofen, a nonsteroidal anti-inflammatory, is the less active enantiomer of ibuprofen, an inhibitor of Cox-1 and Cox-2.An inhibitor of Cox-1 and Cox-2.