ligands acting on targets

(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC 50 of 66 nM and a K d of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC 50 of

(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC 50 of 66 nM and a K d of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC 50 of

(Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR , respectively.In VitroCP-601927 induces significant antidepressant-like effects in mice. CP-601927

(Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR , respectively.In VitroCP-601927 induces significant antidepressant-like effects in mice. CP-601927

(Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR , respectively.In VitroCP-601927 induces significant antidepressant-like effects in mice. CP-601927

(Rac)-E1R (Compound 2) is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric modulator ( Sig1R PAM ) used for the research of cognition/memory disorders.In VitroSigma-1 receptor plays an important role in neuronal plasticity, a

(Rac)-E1R (Compound 2) is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric modulator ( Sig1R PAM ) used for the research of cognition/memory disorders.In VitroSigma-1 receptor plays an important role in neuronal plasticity, a

(Rac)-E1R (Compound 2) is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric modulator ( Sig1R PAM ) used for the research of cognition/memory disorders.In VitroSigma-1 receptor plays an important role in neuronal plasticity, a

(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a K i of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia

(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a K i of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia

(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a K i of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia

(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a K i of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia