ligands acting on targets

15(S)-HETE-biotin is a major arachidonic acid metabolite produced by the 15-LO (15-lipoxygenase) pathway and is characterized as a potent inhibitor of 5-LO. The mechanism by which 15(S)-HETE acts as a leukotriene inhibitor is not clear. In studies

15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC|50|value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE .

15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC|50|value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE .

15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC|50|value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE .

A solution in ethanol. To change the solvent, simply evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice.

15-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-11-oxa-3,4,6,19,24-pentazatetracyclo[18.3.1.02,6.012,17]tetracosa-1(24),2,4,12(17),13,15,20,22-octaen-18-one.

15-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-11-oxa-3,4,6,19,24-pentazatetracyclo[18.3.1.02,6.012,17]tetracosa-1(24),2,4,12(17),13,15,20,22-octaen-18-one.

15-Acetoxyscirpenol, yet another trichothecene class mycotoxin, is a hydrolysis product of Diacetoxyscirpenol.

15-Acetoxyscirpenol, yet another trichothecene class mycotoxin, is a hydrolysis product of Diacetoxyscirpenol.

15-Acetoxyscirpenol, yet another trichothecene class mycotoxin, is a hydrolysis product of Diacetoxyscirpenol.

An analog of PGF2α with resistance to 15-hydroxy PGDH metabolism. Binds to the FP receptor on ovine luteal cells with a relative affinity of 46% in comparison to PGF2α.

An analog of PGF2α with resistance to 15-hydroxy PGDH metabolism. Binds to the FP receptor on ovine luteal cells with a relative affinity of 46% in comparison to PGF2α.