Activin and Inhibin

AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC 50 of 18 nM and a K d of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4 , TGFBR1 , and ALK7 . AZ12601011 inhibits mammary tumor

AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC 50 of 18 nM and a K d of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4 , TGFBR1 , and ALK7 . AZ12601011 inhibits mammary tumor

AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC 50 of 18 nM and a K d of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4 , TGFBR1 , and ALK7 . AZ12601011 inhibits mammary tumor

AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC 50 of 18 nM and a K d of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4 , TGFBR1 , and ALK7 . AZ12601011 inhibits mammary tumor

AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC 50 of 18 nM and a K d of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4 , TGFBR1 , and ALK7 . AZ12601011 inhibits mammary tumor

AZ12672857 is an orally active inhibitor of EphB4 ( IC 50 =1.3 nM) and Src kinases . AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC 50 =2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells

AZ12672857 is an orally active inhibitor of EphB4 ( IC 50 =1.3 nM) and Src kinases . AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC 50 =2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells

AZ12672857 is an orally active inhibitor of EphB4 ( IC 50 =1.3 nM) and Src kinases . AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC 50 =2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells

AZ12672857 is an orally active inhibitor of EphB4 ( IC 50 =1.3 nM) and Src kinases . AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC 50 =2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells

AZ12672857 is an orally active inhibitor of EphB4 ( IC 50 =1.3 nM) and Src kinases . AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC 50 =2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells

AZ12672857 is an orally active inhibitor of EphB4 ( IC 50 =1.3 nM) and Src kinases . AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC 50 =2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells

AZ13705339 hemihydrate is a highly potent and selective PAK1 inhibitor with IC 50 s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2 , with K d s of 0.28 nM and 0.32 nM,