-
C656646-1mlCLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). CLP-3094 inhibits AR transcriptional activity (IC 50 =4 μM). CLP-3094 is a selective, potent GPR142 antagonist .In VitroCLP-3094 inhibits both an
-
C659211-100mgCM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT , with IC 50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer
-
C659211-10mgCM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT , with IC 50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer
-
C659211-50mgCM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT , with IC 50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer
-
C659211-5mgCM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT , with IC 50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer
-
C661672-1mlCM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT , with IC 50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells.IC50&: Target:DNA
-
C649600-10mgCM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases -selective inhibitor, with IC 50 values of 114 nM and 673 nM for PDE5 and HDAC1 , respectively. CM-675 has potential to treat Alzheimer’s diseaseIn VitroCM-675 (29a) shows
-
C649600-5mgCM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases -selective inhibitor, with IC 50 values of 114 nM and 673 nM for PDE5 and HDAC1 , respectively. CM-675 has potential to treat Alzheimer’s diseaseIn VitroCM-675 (29a) shows
-
C655920-1mlCM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases -selective inhibitor, with IC 50 values of 114 nM and 673 nM for PDE5 and HDAC1 , respectively. CM-675 has potential to treat Alzheimer’s diseaseIn VitroCM-675 (29a) shows
-
C650614-100mgCM398 is a highly selective, orally active sigma-2 receptor ligand ( K i =0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). CM398
-
C650614-10mgCM398 is a highly selective, orally active sigma-2 receptor ligand ( K i =0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). CM398
-
C650614-25mgCM398 is a highly selective, orally active sigma-2 receptor ligand ( K i =0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). CM398