Activin and Inhibin

CMF019 is a potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of

CMLD-2, an inhibitor of HuR-ARE interaction , competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs ( K i =350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different

CMLD-2, an inhibitor of HuR-ARE interaction , competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs ( K i =350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different

CMLD-2, an inhibitor of HuR-ARE interaction , competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs ( K i =350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different

CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC 50 value of 2 nM. CMLD012612

CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC 50 value of 2 nM. CMLD012612

CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1 , PRMT4 , and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5

CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1 , PRMT4 , and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5

CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1 , PRMT4 , and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5

CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1 , PRMT4 , and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5

CMPD-39 is a selective USP30 inhibitor with an IC 50 of 0.02 μM. CMPD-39 increases protein ubiquitination and accelerates mitophagyForm:SolidIC50&amp: Target:USP30 0.02 μM (IC 50 ).

CMPD-39 is a selective USP30 inhibitor with an IC 50 of 0.02 μM. CMPD-39 increases protein ubiquitination and accelerates mitophagyForm:SolidIC50&amp: Target:USP30 0.02 μM (IC 50 ).