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C647904-50mgCNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor with IC 50 of 6.8 nM.In VitroCNX-1351 is able to potently (EC 50 <:100 nM) and specifically inhibit signaling in PI3Kα-dependent cancer cell lines, and this leads to a
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C647904-5mgCNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor with IC 50 of 6.8 nM.In VitroCNX-1351 is able to potently (EC 50 <:100 nM) and specifically inhibit signaling in PI3Kα-dependent cancer cell lines, and this leads to a
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C655216-1mlCNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor with IC 50 of 6.8 nM.In VitroCNX-1351 is able to potently (EC 50 <:100 nM) and specifically inhibit signaling in PI3Kα-dependent cancer cell lines, and this leads to a
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C649591-10mgCO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrierIn VivoCO23 (ip: 0.04-5.0 nmol/g) has ≈50% cholesterol reduction with 0.8
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C649591-5mgCO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrierIn VivoCO23 (ip: 0.04-5.0 nmol/g) has ≈50% cholesterol reduction with 0.8
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C648646-10mgCobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC 50 value against MEK1 is 4.2 nM.In VitroThe EC 50 values of Cobimetinib (GDC-0973) for 888MEL and A2058 cells are 0.2 μM, 10 μM, respectivelly. Melanoma cells are treated with
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C648646-2mgCobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC 50 value against MEK1 is 4.2 nM.In VitroThe EC 50 values of Cobimetinib (GDC-0973) for 888MEL and A2058 cells are 0.2 μM, 10 μM, respectivelly. Melanoma cells are treated with
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C648646-50mgCobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC 50 value against MEK1 is 4.2 nM.In VitroThe EC 50 values of Cobimetinib (GDC-0973) for 888MEL and A2058 cells are 0.2 μM, 10 μM, respectivelly. Melanoma cells are treated with
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C648646-5mgCobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC 50 value against MEK1 is 4.2 nM.In VitroThe EC 50 values of Cobimetinib (GDC-0973) for 888MEL and A2058 cells are 0.2 μM, 10 μM, respectivelly. Melanoma cells are treated with
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C655512-1mlCobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC 50 value against MEK1 is 4.2 nM.In VitroThe EC 50 values of Cobimetinib (GDC-0973) for 888MEL and A2058 cells are 0.2 μM, 10 μM, respectivelly. Melanoma cells are treated with
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C649329-10mgCobimetinib racemate (GDC-0973 racemate: XL518 racemate) is the racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor .Form:Solid.
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C649329-1mgCobimetinib racemate (GDC-0973 racemate: XL518 racemate) is the racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor .Form:Solid.