Activin and Inhibin

DI-1859 is a potent, selective and covalent inhibitor of DCN1. DI-1859 inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 induces a robust increase of NRF2 protein, a CRL3 substrate, in mouse liver and effectively

DI-1859 is a potent, selective and covalent inhibitor of DCN1. DI-1859 inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 induces a robust increase of NRF2 protein, a CRL3 substrate, in mouse liver and effectively

DI-591 is a potent, high-affinity and cell-permeable inhibitor of the DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with K i values of 12 nM and 10.4 nM, respectively and has no appreciable binding to DCN3, DCN4, and DCN5 proteins. DI-591

DI-591 is a potent, high-affinity and cell-permeable inhibitor of the DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with K i values of 12 nM and 10.4 nM, respectively and has no appreciable binding to DCN3, DCN4, and DCN5 proteins. DI-591

Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295 nm. Antithrombotic efficacy.In VitroPAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved

Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295 nm. Antithrombotic efficacy.In VitroPAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved

Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295 nm. Antithrombotic efficacy.In VitroPAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved

Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295 nm. Antithrombotic efficacy.In VitroPAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved

Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295 nm. Antithrombotic efficacy.In VitroPAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved

Dicentrine is a natural product isolated from the plant Stephania epigaea Lo with antihypertensive effect. Dicentrine is an α 1 -adrenoceptor antagonist which has effective against human hyperplastic prostatesForm:SolidIC50&amp: Target:α adrenergic

Dicentrine is a natural product isolated from the plant Stephania epigaea Lo with antihypertensive effect. Dicentrine is an α 1 -adrenoceptor antagonist which has effective against human hyperplastic prostatesForm:SolidIC50&amp: Target:α adrenergic

Dichlorophenyl-ABA is an inhibitor of transthyretin (TTR) amyloid fibril formation , inhibiting aggregate formation in more than 80% in TTR L55P-expressing cellsIn VitroDichlorophenyl-ABA (DCPA) is able to prevent L55P aggregate formation in the