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D658712-10mgDot1L-IN-1 TFA is a highly potent and selective Dot1L inhibitor with a K i of 2 pM and an IC 50 of <:0.1 nM. Dot1L-IN-1 TFA potently suppresses H3K79 dimethylation (IC 50 =3 nM), as well as the activity of the HoxA9 promoter (IC 50 =17 nM) in HeLa
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D658712-1mgDot1L-IN-1 TFA is a highly potent and selective Dot1L inhibitor with a K i of 2 pM and an IC 50 of <:0.1 nM. Dot1L-IN-1 TFA potently suppresses H3K79 dimethylation (IC 50 =3 nM), as well as the activity of the HoxA9 promoter (IC 50 =17 nM) in HeLa
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D658712-5mgDot1L-IN-1 TFA is a highly potent and selective Dot1L inhibitor with a K i of 2 pM and an IC 50 of <:0.1 nM. Dot1L-IN-1 TFA potently suppresses H3K79 dimethylation (IC 50 =3 nM), as well as the activity of the HoxA9 promoter (IC 50 =17 nM) in HeLa
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D648943-10mgDot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 SPA DOT1L of 0.11 nMIn VitroDot1L-IN-4 (Compound 10) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in
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D648943-1mgDot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 SPA DOT1L of 0.11 nMIn VitroDot1L-IN-4 (Compound 10) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in
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D648943-25mgDot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 SPA DOT1L of 0.11 nMIn VitroDot1L-IN-4 (Compound 10) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in
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D648943-5mgDot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 SPA DOT1L of 0.11 nMIn VitroDot1L-IN-4 (Compound 10) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in
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D655640-1mlDot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 SPA DOT1L of 0.11 nMIn VitroDot1L-IN-4 (Compound 10) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in
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D646409-10mgDot1L-IN-5 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 of 0.17 nMIn VitroDot1L-IN-5 (Compound 11) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in HeLa
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D646409-25mgDot1L-IN-5 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 of 0.17 nMIn VitroDot1L-IN-5 (Compound 11) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in HeLa
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D646409-5mgDot1L-IN-5 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 of 0.17 nMIn VitroDot1L-IN-5 (Compound 11) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in HeLa
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D654571-1mlDot1L-IN-5 is a potent disruptor of telomeric silencing 1-like protein ( DOT1L ) inhibitor with an IC 50 of 0.17 nMIn VitroDot1L-IN-5 (Compound 11) is tested in cellular assays to assess the ability to inhibit the dimethylation of H3K79 in HeLa