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D647615-50mgDS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC 50 value of 0.0063 μM. DS18561882 also has inhibitory effect on MTHFD1 ( IC 50 =0.57 μM). DS18561882 exhibits a good oral
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D647615-5mgDS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC 50 value of 0.0063 μM. DS18561882 also has inhibitory effect on MTHFD1 ( IC 50 =0.57 μM). DS18561882 exhibits a good oral
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D655105-1mlDS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC 50 value of 0.0063 μM. DS18561882 also has inhibitory effect on MTHFD1 ( IC 50 =0.57 μM). DS18561882 exhibits a good oral
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D650049-10mgDS20362725 is an estrogen-related receptor α ( ERRα ) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD: 1.2 μM) with an IC 50 value of 0.6
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D650049-50mgDS20362725 is an estrogen-related receptor α ( ERRα ) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD: 1.2 μM) with an IC 50 value of 0.6
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D650049-5mgDS20362725 is an estrogen-related receptor α ( ERRα ) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD: 1.2 μM) with an IC 50 value of 0.6
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D656112-1mlDS20362725 is an estrogen-related receptor α ( ERRα ) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD: 1.2 μM) with an IC 50 value of 0.6
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D646229-10mgDS44960156 is a selective Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor, with IC 50 values of 1.6 μM and >:30 μM for MTHFD2 and MTHFD1, respectivelyForm:SolidIC50&: Target:IC50: 1.6 μM (MTHFD2), >:30 μM (MTHFD1).
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D646229-25mgDS44960156 is a selective Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor, with IC 50 values of 1.6 μM and >:30 μM for MTHFD2 and MTHFD1, respectivelyForm:SolidIC50&: Target:IC50: 1.6 μM (MTHFD2), >:30 μM (MTHFD1).
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D646229-50mgDS44960156 is a selective Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor, with IC 50 values of 1.6 μM and >:30 μM for MTHFD2 and MTHFD1, respectivelyForm:SolidIC50&: Target:IC50: 1.6 μM (MTHFD2), >:30 μM (MTHFD1).
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D646229-5mgDS44960156 is a selective Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor, with IC 50 values of 1.6 μM and >:30 μM for MTHFD2 and MTHFD1, respectivelyForm:SolidIC50&: Target:IC50: 1.6 μM (MTHFD2), >:30 μM (MTHFD1).
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D646653-10mgDS45500853 is an estrogen-related receptor α ( ERRα ) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD: 1.2 μM) with an IC 50 value of 0.80