Activin and Inhibin

EM127 (compound 11c) is a SMYD3 covalent inhibitor with high selectivity, high affinity ( K D =13 μM) and site-specificity. EM127 effectively inhibits ERK1/2 phosphorylation and reduces transcriptional regulation of SMYD3 target genes. EM127

EMAC10101d is a potent and selective toward hCA II inhibitor, with a K i of 8.1 nM.In VitroEMAC10101d exhibits K i values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. MCE has not independently

EMAC10101d is a potent and selective toward hCA II inhibitor, with a K i of 8.1 nM.In VitroEMAC10101d exhibits K i values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. MCE has not independently

EMAC10101d is a potent and selective toward hCA II inhibitor, with a K i of 8.1 nM.In VitroEMAC10101d exhibits K i values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. MCE has not independently

EMAC10101d is a potent and selective toward hCA II inhibitor, with a K i of 8.1 nM.In VitroEMAC10101d exhibits K i values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. MCE has not independently

EMAC10101d is a potent and selective toward hCA II inhibitor, with a K i of 8.1 nM.In VitroEMAC10101d exhibits K i values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. MCE has not independently

EMAC10101d is a potent and selective toward hCA II inhibitor, with a K i of 8.1 nM.In VitroEMAC10101d exhibits K i values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. MCE has not independently

EMAC10101d is a potent and selective toward hCA II inhibitor, with a K i of 8.1 nM.In VitroEMAC10101d exhibits K i values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. MCE has not independently

EMD534085 is a potent and selective inhibitor of the mitotic kinesin-5 with an IC 50 of 8 nM.In VitroEMD 534085 does not inhibit any other tested kinesins (BimC, CEN-PE, Chromokinesin, KHC, KIF3C, KIFC3, MKLP-1, and MCAK) at 1 μM or 10 μM

EMD534085 is a potent and selective inhibitor of the mitotic kinesin-5 with an IC 50 of 8 nM.In VitroEMD 534085 does not inhibit any other tested kinesins (BimC, CEN-PE, Chromokinesin, KHC, KIF3C, KIFC3, MKLP-1, and MCAK) at 1 μM or 10 μM

EMD534085 is a potent and selective inhibitor of the mitotic kinesin-5 with an IC 50 of 8 nM.In VitroEMD 534085 does not inhibit any other tested kinesins (BimC, CEN-PE, Chromokinesin, KHC, KIF3C, KIFC3, MKLP-1, and MCAK) at 1 μM or 10 μM

EMD534085 is a potent and selective inhibitor of the mitotic kinesin-5 with an IC 50 of 8 nM.In VitroEMD 534085 does not inhibit any other tested kinesins (BimC, CEN-PE, Chromokinesin, KHC, KIF3C, KIFC3, MKLP-1, and MCAK) at 1 μM or 10 μM