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G650127-50mgGPR40 agonist 6 (Compound 7a) is a potent and selective free fatty acid receptor 1 ( FFAR1 or GPR40 ) agonist with an EC 50 of 0.058 μMIn VitroGPR40 agonist 6 (Compound 7a) shows a very favorable ADME profile, and shows no significant inhibition of
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G650127-5mgGPR40 agonist 6 (Compound 7a) is a potent and selective free fatty acid receptor 1 ( FFAR1 or GPR40 ) agonist with an EC 50 of 0.058 μMIn VitroGPR40 agonist 6 (Compound 7a) shows a very favorable ADME profile, and shows no significant inhibition of
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G656141-1mlGPR40 agonist 6 (Compound 7a) is a potent and selective free fatty acid receptor 1 ( FFAR1 or GPR40 ) agonist with an EC 50 of 0.058 μMIn VitroGPR40 agonist 6 (Compound 7a) shows a very favorable ADME profile, and shows no significant inhibition of
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G649331-100mgGPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)Form:SolidIC50&: Target:Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1).
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G649331-10mgGPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)Form:SolidIC50&: Target:Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1).
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G649331-25mgGPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)Form:SolidIC50&: Target:Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1).
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G649331-500mgGPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)Form:SolidIC50&: Target:Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1).
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G649331-50mgGPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)Form:SolidIC50&: Target:Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1).
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G649331-5mgGPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)Form:SolidIC50&: Target:Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1).
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G646321-10mgGPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.In VitroGPX4-IN-3 (26a) exhibits IC 50 values of 0.78 μM, 6.9 μM, 0.15 μM and 4.73
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G646321-25mgGPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.In VitroGPX4-IN-3 (26a) exhibits IC 50 values of 0.78 μM, 6.9 μM, 0.15 μM and 4.73
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G646321-5mgGPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.In VitroGPX4-IN-3 (26a) exhibits IC 50 values of 0.78 μM, 6.9 μM, 0.15 μM and 4.73