Activin and Inhibin

GRK6-IN-2 (compound 10a) is a potent inhibitor of G protein-coupled receptor kinase 6 ( GRK6 ) with an IC 50 of 120 nM. GRK6 is a critical kinase required for the survival of multiple myeloma (MM) cells. GRK6-IN-2 has the potential for the research

GRP-60367 hydrochloride is a first-in-class small-molecule rabies virus ( RABV ) entry inhibitor with nanomolar potency against some RABV strains. GRP-60367 hydrochloride specifically targets the RABV G protein.In Vitro:GRP-60367 (0.1 nM-1000 μM)

Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC 50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90αIn VitroGrp94-specific clients include a subset of integrin subunits such as integrin α2 and integrin αL.

Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC 50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90αIn VitroGrp94-specific clients include a subset of integrin subunits such as integrin α2 and integrin αL.

Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC 50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90αIn VitroGrp94-specific clients include a subset of integrin subunits such as integrin α2 and integrin αL.

Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC 50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90αIn VitroGrp94-specific clients include a subset of integrin subunits such as integrin α2 and integrin αL.

Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC 50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90αIn VitroGrp94-specific clients include a subset of integrin subunits such as integrin α2 and integrin αL.

GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC 50 s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite

GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC 50 s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite

GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC 50 s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite

GS-626510 is a potent, and orally active BET family bromodomains inhibitor, with K d values of 0.59-3.2 nM for BRD2/3/4, with IC 50 values of 83 nM and 78 nM foe BD1 and BD2 , respectivelyForm:SolidIC50&amp: Target:BRD2 0.59-2.5 nM (Kd) BRD3

GS-626510 is a potent, and orally active BET family bromodomains inhibitor, with K d values of 0.59-3.2 nM for BRD2/3/4, with IC 50 values of 83 nM and 78 nM foe BD1 and BD2 , respectivelyForm:SolidIC50&amp: Target:BRD2 0.59-2.5 nM (Kd) BRD3