Activin and Inhibin

GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC proteinIn VitroGW284543 (10 and 20 μM: 6 h) treatment inhibits MEK5 in a dose-dependent manner and reduces pERK5. MCE has not independently

GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC proteinIn VitroGW284543 (10 and 20 μM: 6 h) treatment inhibits MEK5 in a dose-dependent manner and reduces pERK5. MCE has not independently

GW-311616 is a potent, orally bioavailable, long duration and selective human neutrophil elastase ( HNE ) inhibitor with IC 50 value of 22 nM and K i value of 0.31 nMIn VitroGW-311616 (150 μM: 48 hours) markedly suppresses NE activity in U937 and

GW-311616 is a potent, orally bioavailable, long duration and selective human neutrophil elastase ( HNE ) inhibitor with IC 50 value of 22 nM and K i value of 0.31 nMIn VitroGW-311616 (150 μM: 48 hours) markedly suppresses NE activity in U937 and

GW-311616 is a potent, orally bioavailable, long duration and selective human neutrophil elastase ( HNE ) inhibitor with IC 50 value of 22 nM and K i value of 0.31 nMIn VitroGW-311616 (150 μM: 48 hours) markedly suppresses NE activity in U937 and

GW-311616 is a potent, orally bioavailable, long duration and selective human neutrophil elastase ( HNE ) inhibitor with IC 50 value of 22 nM and K i value of 0.31 nMIn VitroGW-311616 (150 μM: 48 hours) markedly suppresses NE activity in U937 and

GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents.In VivoGW438014A (10 mg/kg: i.p.: daily, for 7 d) inhibits spontaneous as well as overnight fasting-induced

GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents.In VivoGW438014A (10 mg/kg: i.p.: daily, for 7 d) inhibits spontaneous as well as overnight fasting-induced

GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents.In VivoGW438014A (10 mg/kg: i.p.: daily, for 7 d) inhibits spontaneous as well as overnight fasting-induced

GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents.In VivoGW438014A (10 mg/kg: i.p.: daily, for 7 d) inhibits spontaneous as well as overnight fasting-induced

GW7604 is an antiestrogen. GW7604 is the metabolite of GW5638, which is a high affinity estrogen receptor (ER) antagonist.In VitroGW7604 is the presumed metabolite of GW5638 in breast (MCF-7) and endometrial (ECC-1) cell lines. GW7604 (0.1 nM-1 μM:

GW779439X is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1 . GW779439X potentiates the activity of β-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to