Activin and Inhibin

HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activityIn VitroHDAC-IN-4 inhibits HDAC1, HDAC2, HDAC3, HDAC8 and HDAC10 with pIC 50 s of 5.5, 4.6, 5.4, 5.4, 6.7 in FRET

HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activityIn VitroHDAC-IN-4 inhibits HDAC1, HDAC2, HDAC3, HDAC8 and HDAC10 with pIC 50 s of 5.5, 4.6, 5.4, 5.4, 6.7 in FRET

HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activityIn VitroHDAC-IN-4 inhibits HDAC1, HDAC2, HDAC3, HDAC8 and HDAC10 with pIC 50 s of 5.5, 4.6, 5.4, 5.4, 6.7 in FRET

HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activityIn VitroHDAC-IN-4 inhibits HDAC1, HDAC2, HDAC3, HDAC8 and HDAC10 with pIC 50 s of 5.5, 4.6, 5.4, 5.4, 6.7 in FRET

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.In VitroHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.In VitroHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.In VitroHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.In VitroHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.In VitroHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.In VitroHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.In VitroHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines

HDACs/mTOR Inhibitor 1 is a dual HDACs and mTOR inhibitor, with IC 50 s of 0.19 nM, 1.8 nM, 1.2 nM for HDAC1 , HDAC6 , mTOR , respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induces tumor cell apoptosis with low