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H658896-5mgHPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1: MAP4K1) inhibitor with an IC 50 of 0.25 nM. HPK1-IN-3 has IL-2 cellular potency with an EC 50 of 108 nM in human peripheral blood mononuclear cells
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H661616-1mlHPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1: MAP4K1) inhibitor with an IC 50 of 0.25 nM. HPK1-IN-3 has IL-2 cellular potency with an EC 50 of 108 nM in human peripheral blood mononuclear cells
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H651434-10mgHPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC 50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseasesIn VitroHPK1-IN-32 (Example A34, 0-2 μM, 2 h) inhibits cellular pSLP76 activity with an IC 50 of
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H651434-25mgHPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC 50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseasesIn VitroHPK1-IN-32 (Example A34, 0-2 μM, 2 h) inhibits cellular pSLP76 activity with an IC 50 of
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H651434-5mgHPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC 50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseasesIn VitroHPK1-IN-32 (Example A34, 0-2 μM, 2 h) inhibits cellular pSLP76 activity with an IC 50 of
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H646141-10mgHPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 ( HPK1 ) inhibitor with an IC 50 of <:100 nMForm:SolidIC50&: Target:HPK1 <:100 nM (IC 50 ).
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H646141-25mgHPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 ( HPK1 ) inhibitor with an IC 50 of <:100 nMForm:SolidIC50&: Target:HPK1 <:100 nM (IC 50 ).
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H646141-5mgHPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 ( HPK1 ) inhibitor with an IC 50 of <:100 nMForm:SolidIC50&: Target:HPK1 <:100 nM (IC 50 ).
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H646496-10mgHPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor ( IC 50 of 0.061 nM) as preclinical immunoresearch tool compoundForm:SolidIC50&: Target:IC50: 0.061 nM (HPK1).
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H646496-5mgHPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor ( IC 50 of 0.061 nM) as preclinical immunoresearch tool compoundForm:SolidIC50&: Target:IC50: 0.061 nM (HPK1).
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H654603-1mlHPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor ( IC 50 of 0.061 nM) as preclinical immunoresearch tool compoundIC50&: Target:IC50: 0.061 nM (HPK1).
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H648327-10mgHPK1-IN-7 is a potent, orally active HPK1 (hematopoietic progenitor kinase 1, MAP4K1) inhibitor ( IC 50 =2.6 nM) with excellent family and kinome selectivity. HPK1-IN-7 shows selectivity against IRAK4 (59 nM) and GLK (140 nM). HPK1-IN-7 shows robust