Activin and Inhibin

I-BET282 is a pan-inhibitor of all eight BET bromodomains , and selectivity over other representative bromodomain-containing proteins. I-BET282 shows pIC 50 s ranging 6.4-7.7 for BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), and BRD4 (BD1/BD).In

I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC 50 s of 6.9 and 7.2 for BRD4 BD1 and BD2 , respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammationIn VitroI-BET567 (compound

I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC 50 s of 6.9 and 7.2 for BRD4 BD1 and BD2 , respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammationIn VitroI-BET567 (compound

IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia

IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia

IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia

IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia

IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia

IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia

IACS-8968 (IDO/TDO Inhibitor) is a dual IDO and TDO inhibitor, with pIC 50 s of 6.43 for IDO and &lt:5 for TDO, respectively.Form:SolidIC50&amp: Target:pIC50: 6.43 (IDO), &lt:5 (TDO).

IACS-8968 (IDO/TDO Inhibitor) is a dual IDO and TDO inhibitor, with pIC 50 s of 6.43 for IDO and &lt:5 for TDO, respectively.Form:SolidIC50&amp: Target:pIC50: 6.43 (IDO), &lt:5 (TDO).

IACS-8968 (IDO/TDO Inhibitor) is a dual IDO and TDO inhibitor, with pIC 50 s of 6.43 for IDO and &lt:5 for TDO, respectively.Form:SolidIC50&amp: Target:pIC50: 6.43 (IDO), &lt:5 (TDO).