Activin and Inhibin

M-89 is a highly potent and specific menin inhibitor, with a K d of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemiaForm:SolidIC50&amp:

M-89 is a highly potent and specific menin inhibitor, with a K d of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemiaForm:SolidIC50&amp:

M1002 is a hypoxia-inducible factor-2 ( HIF-2 ) agonist, and can enhance the expression of HIF-2 target genes. M1002 shows synergy with prolyl-hydroxylase domain (PHD) inhibitors.In VitroM1002 (10 μM: 24 h) enhances the expression of HIF-2 target

M2698 (MSC2363318A) is an orally active, ATP competitive, selective p70S6K and Akt dual-inhibitor with IC 50 s of 1 nM for p70S6K , Akt1 and Akt3 . M2698 can cross the blood-brain barrier and has anti-cancer activityIn VitroM2698 (0.3 nM to 50 M: 72

M2698 (MSC2363318A) is an orally active, ATP competitive, selective p70S6K and Akt dual-inhibitor with IC 50 s of 1 nM for p70S6K , Akt1 and Akt3 . M2698 can cross the blood-brain barrier and has anti-cancer activityIn VitroM2698 (0.3 nM to 50 M: 72

M2698 (MSC2363318A) is an orally active, ATP competitive, selective p70S6K and Akt dual-inhibitor with IC 50 s of 1 nM for p70S6K , Akt1 and Akt3 . M2698 can cross the blood-brain barrier and has anti-cancer activityIn VitroM2698 (0.3 nM to 50 M: 72

M2698 (MSC2363318A) is an orally active, ATP competitive, selective p70S6K and Akt dual-inhibitor with IC 50 s of 1 nM for p70S6K , Akt1 and Akt3 . M2698 can cross the blood-brain barrier and has anti-cancer activityIn VitroM2698 (0.3 nM to 50 M: 72

M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC 50 value of 0.09  μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC 50 values of  0.53  μM and 1.39 μM,

M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC 50 value of 0.09  μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC 50 values of  0.53  μM and 1.39 μM,

M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC 50 value of 0.09  μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC 50 values of  0.53  μM and 1.39 μM,

M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC 50 value of 0.09  μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC 50 values of  0.53  μM and 1.39 μM,

M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC 50 value of 0.09  μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC 50 values of  0.53  μM and 1.39 μM,