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A649418-5mgAAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3 Ser10 phosphorylation and followed by a surge in apoptosis
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A649141-100mgAAT-008 is a potent, selective, and orally active prostaglandin EP4 receptor antagonist with K i s of 0.97 and 6.1 nM for recombinant human EP4 and recombinant rat EP4, respectivelyForm:SolidIC50&: Target:EP4 0.97 nM (Ki) EP4 6.1 nM (IC 50 ).
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A649141-10mgAAT-008 is a potent, selective, and orally active prostaglandin EP4 receptor antagonist with K i s of 0.97 and 6.1 nM for recombinant human EP4 and recombinant rat EP4, respectivelyForm:SolidIC50&: Target:EP4 0.97 nM (Ki) EP4 6.1 nM (IC 50 ).
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A649141-25mgAAT-008 is a potent, selective, and orally active prostaglandin EP4 receptor antagonist with K i s of 0.97 and 6.1 nM for recombinant human EP4 and recombinant rat EP4, respectivelyForm:SolidIC50&: Target:EP4 0.97 nM (Ki) EP4 6.1 nM (IC 50 ).
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A649141-50mgAAT-008 is a potent, selective, and orally active prostaglandin EP4 receptor antagonist with K i s of 0.97 and 6.1 nM for recombinant human EP4 and recombinant rat EP4, respectivelyForm:SolidIC50&: Target:EP4 0.97 nM (Ki) EP4 6.1 nM (IC 50 ).
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A649141-5mgAAT-008 is a potent, selective, and orally active prostaglandin EP4 receptor antagonist with K i s of 0.97 and 6.1 nM for recombinant human EP4 and recombinant rat EP4, respectivelyForm:SolidIC50&: Target:EP4 0.97 nM (Ki) EP4 6.1 nM (IC 50 ).
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A648992-10mgAB-836 is an orally active HBV capsid inhibitor. AB-836 inhibits viral replication by interacting with HBV core protein.Form:Solid.
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A648992-5mgAB-836 is an orally active HBV capsid inhibitor. AB-836 inhibits viral replication by interacting with HBV core protein.Form:Solid.
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A654737-1mlAbarelix Acetate (PPI 149 Acetate: R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer researchIC50&: Target:GnRH.
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A646953-1mgABBV-CLS-484 is a potent PTPN1 and PTPN2 inhibitor with subnanomolar activity. ABBV-CLS-484 has antitumor activity, enhances the immune response and increases the sensitivity of tumors to immune-mediated killing.In VitroABBV-CLS-484 acts on both
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A646953-5mgABBV-CLS-484 is a potent PTPN1 and PTPN2 inhibitor with subnanomolar activity. ABBV-CLS-484 has antitumor activity, enhances the immune response and increases the sensitivity of tumors to immune-mediated killing.In VitroABBV-CLS-484 acts on both
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A659421-10mgABD957 is a potent and selective covalent inhibitor of the ABHD17 family of depalmitoylases, with an IC 50 of 0.21 µM for ABHD17B . ABD957 can block N-Ras signaling and the growth of NRAS-mutant AML cells.Appearance:SolidIC50&: Target:IC50: 0.21