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A655267-1mlAKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity.In VitroThe effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a
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A647070-10mgAKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1 , Akt2 and Akt3 , respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family
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A647070-5mgAKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1 , Akt2 and Akt3 , respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family
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A649162-100mgAkt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the
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A649162-10mgAkt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the
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A649162-50mgAkt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the
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A649162-5mgAkt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the
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A655734-1mlAkt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the
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A658785-1mgAlbiglutide fragment (GLP-1 (7-36) analog) TFA is an active fragment of Albiglutide (7-36) and a Glukagon-like peptide-1 (GLP-1) analog (a long-acting GLP-1 receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with
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A658785-5mgAlbiglutide fragment (GLP-1 (7-36) analog) TFA is an active fragment of Albiglutide (7-36) and a Glukagon-like peptide-1 (GLP-1) analog (a long-acting GLP-1 receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with
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A648011-10mgALDH1A1-IN-2 is a potent inhibitor of aldehyde dehydrogenase 1a1 ( aldh1a1 ). Aldehyde dehydrogenases (ALDH) constitute a family of enzymes that play a critical role in oxidizing various cytotoxic xenogenic and biogenic aldehydes. ALDH1A1-IN-2 has
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A648011-25mgALDH1A1-IN-2 is a potent inhibitor of aldehyde dehydrogenase 1a1 ( aldh1a1 ). Aldehyde dehydrogenases (ALDH) constitute a family of enzymes that play a critical role in oxidizing various cytotoxic xenogenic and biogenic aldehydes. ALDH1A1-IN-2 has