Approved Ligands

InformationFenoterol (Phenoterol) is aβ2 adrenoreceptoragonist with bronchodilator activity.Targetsβ2 adrenoreceptor.

Application:The active metabolite of Terfenadine, a H1-histamine receptor antagonist.

Application:The active metabolite of Terfenadine, a H1-histamine receptor antagonist.

Application:The active metabolite of Terfenadine, a H1-histamine receptor antagonist.

Application:The active metabolite of Terfenadine, a H1-histamine receptor antagonist.

InformationFilgotinib (GLPG0634) is a selectiveJAK1inhibitor withIC50of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.TargetsJAK1 (Cell-free assay): JAK2 (Cell-free assay): TYK2 (Cell-free assay): JAK3

InformationFilgotinib (GLPG0634) is a selectiveJAK1inhibitor withIC50of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.TargetsJAK1 (Cell-free assay): JAK2 (Cell-free assay): TYK2 (Cell-free assay): JAK3

InformationFilgotinib (GLPG0634) is a selectiveJAK1inhibitor withIC50of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.TargetsJAK1 (Cell-free assay): JAK2 (Cell-free assay): TYK2 (Cell-free assay): JAK3

InformationFilgotinib (GLPG0634) is a selectiveJAK1inhibitor withIC50of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.TargetsJAK1 (Cell-free assay): JAK2 (Cell-free assay): TYK2 (Cell-free assay): JAK3

Fingolimod.

Fingolimod.

Fingolimod.