Approved Ligands

Rivaroxaban is an oral, direct inhibitor of Factor X, being developed for the prevention and treatment of arterial and venous thrombosis with a Ki of 0.4 nM. Rivaroxaban also inhibits prothrombinase activity (IC50 = 2.1 nM). Rivaroxaban also shows a

Rivastigmine.

Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by

Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by

Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by

Rotigotine is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.

InformationRucaparib (Rubraca, AG014699, PF01367338) is an inhibitor ofPARPwith Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.TargetsPARP1 (Cell-free assay) 1.4 nM(Ki).

InformationRucaparib (Rubraca, AG014699, PF01367338) is an inhibitor ofPARPwith Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.TargetsPARP1 (Cell-free assay) 1.4 nM(Ki).

InformationRucaparib (Rubraca, AG014699, PF01367338) is an inhibitor ofPARPwith Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.TargetsPARP1 (Cell-free assay) 1.4 nM(Ki).

InformationRucaparib (Rubraca, AG014699, PF01367338) is an inhibitor ofPARPwith Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.TargetsPARP1 (Cell-free assay) 1.4 nM(Ki).

S-(-)-Carbidopa.

S-(-)-Carbidopa.