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A646431-10mgATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.In VitroThe combination of ATN-161 plus 5-FU significantly reduces tumor cell proliferation compared to
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A646431-2mgATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.In VitroThe combination of ATN-161 plus 5-FU significantly reduces tumor cell proliferation compared to
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A646431-50mgATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.In VitroThe combination of ATN-161 plus 5-FU significantly reduces tumor cell proliferation compared to
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A646431-5mgATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.In VitroThe combination of ATN-161 plus 5-FU significantly reduces tumor cell proliferation compared to
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B659154-10mgBIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d <10 pM). BIO5192 hydrate selectively binds to α4β1 ( IC 50 =1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of
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B659154-5mgBIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d <10 pM). BIO5192 hydrate selectively binds to α4β1 ( IC 50 =1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of
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B661664-1mlBIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d <10 pM). BIO5192 hydrate selectively binds to α4β1 ( IC 50 =1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of
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