Complement components and ligands

Pelecopan (BCX9930) is a potent, selective, orally active inhibitor of complement factor D with an IC 50 value of 14.3 nM. Pelecopan can target factor D to prevent both intravascular and extravascular hemolysis in PNH. Pelecopan also be used for

Pelecopan (BCX9930) is a potent, selective, orally active inhibitor of complement factor D with an IC 50 value of 14.3 nM. Pelecopan can target factor D to prevent both intravascular and extravascular hemolysis in PNH. Pelecopan also be used for

PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR CD88 ) antagonist.Appearance:SolidIC50&amp Target:C5aRIn Vitro:A complement activation product, C5a, is known to recruit and activate microglia and astrocytes in vitro by

PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR CD88 ) antagonist.Appearance:SolidIC50&amp Target:C5aRIn Vitro:A complement activation product, C5a, is known to recruit and activate microglia and astrocytes in vitro by

PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR CD88 ) antagonist.Appearance:SolidIC50&amp Target:C5aRIn Vitro:A complement activation product, C5a, is known to recruit and activate microglia and astrocytes in vitro by

PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR CD88 ) antagonist.Appearance:SolidIC50&amp Target:C5aRIn Vitro:A complement activation product, C5a, is known to recruit and activate microglia and astrocytes in vitro by

PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR CD88 ) antagonist.Appearance:SolidIC50&amp Target:C5aRIn Vitro:A complement activation product, C5a, is known to recruit and activate microglia and astrocytes in vitro by

POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration researchIn VitroA derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide

POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration researchIn VitroA derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide

POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration researchIn VitroA derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide

TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist ( EC 50 : mouse TLQP-21=10.3 μM human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1

TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist ( EC 50 : mouse TLQP-21=10.3 μM human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1