Immune checkpoint modulators

belatacept.

CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC 50 of 3 nM and a K i of 1.16 nMIn VitroCCT241533 hydrochloride inhibits CHK2 with an IC 50 of 3 nM and shows minimal cross reactivity against a panel of kinases at 1 μM.

CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC 50 of 3 nM and a K i of 1.16 nMIn VitroCCT241533 hydrochloride inhibits CHK2 with an IC 50 of 3 nM and shows minimal cross reactivity against a panel of kinases at 1 μM.

CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC 50 of 3 nM and a K i of 1.16 nMIn VitroCCT241533 hydrochloride inhibits CHK2 with an IC 50 of 3 nM and shows minimal cross reactivity against a panel of kinases at 1 μM.

CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC 50 of 3 nM and a K i of 1.16 nMIn VitroCCT241533 hydrochloride inhibits CHK2 with an IC 50 of 3 nM and shows minimal cross reactivity against a panel of kinases at 1 μM.

CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC 50 of 3 nM and a K i of 1.16 nMIn VitroCCT241533 hydrochloride inhibits CHK2 with an IC 50 of 3 nM and shows minimal cross reactivity against a panel of kinases at 1 μM.

CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC 50 of 3 nM and a K i of 1.16 nMIn VitroCCT241533 hydrochloride inhibits CHK2 with an IC 50 of 3 nM and shows minimal cross reactivity against a panel of kinases at 1 μM.

CCT244747 is a potent, orally bioavailable and highly selective CHK1 inhibitor, with an IC 50 of 7.7 nM: CCT244747 also abrogates G2 checkpoint with an IC 50 of 29 nM.In VitroCCT244747 poorly inhibits CHK2 (IC 50 &gt:10 μM) and CDK1 (IC 50 &gt:10

CCT244747 is a potent, orally bioavailable and highly selective CHK1 inhibitor, with an IC 50 of 7.7 nM: CCT244747 also abrogates G2 checkpoint with an IC 50 of 29 nM.In VitroCCT244747 poorly inhibits CHK2 (IC 50 &gt:10 μM) and CDK1 (IC 50 &gt:10

CCT244747 is a potent, orally bioavailable and highly selective CHK1 inhibitor, with an IC 50 of 7.7 nM: CCT244747 also abrogates G2 checkpoint with an IC 50 of 29 nM.In VitroCCT244747 poorly inhibits CHK2 (IC 50 &gt:10 μM) and CDK1 (IC 50 &gt:10

CCT244747 is a potent, orally bioavailable and highly selective CHK1 inhibitor, with an IC 50 of 7.7 nM: CCT244747 also abrogates G2 checkpoint with an IC 50 of 29 nM.In VitroCCT244747 poorly inhibits CHK2 (IC 50 &gt:10 μM) and CDK1 (IC 50 &gt:10

CCT244747 is a potent, orally bioavailable and highly selective CHK1 inhibitor, with an IC 50 of 7.7 nM: CCT244747 also abrogates G2 checkpoint with an IC 50 of 29 nM.In VitroCCT244747 poorly inhibits CHK2 (IC 50 &gt:10 μM) and CDK1 (IC 50 &gt:10