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D340482-50mgDBCO-PEG|4|-maleimide is a maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition
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D340482-5mgDBCO-PEG|4|-maleimide is a maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition
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D651774-10mgDBCO-PEG4-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the cleavable linker DBCO-PEG4.Form:SolidIC50&: Target:Auristatin.
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D647121-1mgDBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic , Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VAIn VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE
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D647346-10mgDBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)In
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D647346-5mgDBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)In
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D647675-10mgDBCO-PEG4-VC-PAB-MMAE consists an ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE ( HY-15162 ). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates ( ADC s). MMAE is a synthetic derivative of
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D647675-25mgDBCO-PEG4-VC-PAB-MMAE consists an ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE ( HY-15162 ). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates ( ADC s). MMAE is a synthetic derivative of
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B305226-100mgdBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.
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B305226-10mgdBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.
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B305226-1mgdBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.
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B305226-25mgdBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.