Ligands of Immunopharmacology

Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory.In VitroCell Viability AssayCell Line:

Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory.In VitroCell Viability AssayCell Line:

CL264 is a TLR7 -specific agonist for innate immune signals researchIn VitroToll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7

CL264 is a TLR7 -specific agonist for innate immune signals researchIn VitroToll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7

CL264 is a TLR7 -specific agonist for innate immune signals researchIn VitroToll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7

CL264 is a TLR7 -specific agonist for innate immune signals researchIn VitroToll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7

CL264 is a TLR7 -specific agonist for innate immune signals researchIn VitroToll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7

CL264 is a TLR7 -specific agonist for innate immune signals researchIn VitroToll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7

CU-115 is a potent TLR8 antagonist ( IC 50 =1.04 µM ), and shows selective for TLR8 over TLR7 (IC 50 =&gt50 µM). CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cellsIn VitroIn endosomal and non-endosomal TLR specificity

CU-115 is a potent TLR8 antagonist ( IC 50 =1.04 µM ), and shows selective for TLR8 over TLR7 (IC 50 =&gt50 µM). CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cellsIn VitroIn endosomal and non-endosomal TLR specificity

CU-115 is a potent TLR8 antagonist ( IC 50 =1.04 µM ), and shows selective for TLR8 over TLR7 (IC 50 =&gt50 µM). CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cellsIn VitroIn endosomal and non-endosomal TLR specificity

CU-CPT17e is a potent multi- Toll-like receptor ( TLR ) agonist that activates TLR3 , TLR8 , and TLR9 .In VitroCU-CPT17e shows strong NF-κB activation in TLR3, TLR8 and TLR9 HEK293 cells with EC 50 values of 4.80±0.73, 13.5±0.58 and 5.66±0.17 μM,