Ligands of Immunopharmacology

FAPI-4 is a potent fibroblast activation protein ( FAP ) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. 68 Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer , with good

FAPI-46 is a quinoline-based fibroblast activation protein (FAP) -targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancersIn VitroFAPI-46 (1-24

FAPI-46 is a quinoline-based fibroblast activation protein (FAP) -targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancersIn VitroFAPI-46 (1-24

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) , with IC 50 s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activityIn VitroG140 (0.1-100 μM 4 h) inhibits h-cGAS in a

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) , with IC 50 s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activityIn VitroG140 (0.1-100 μM 4 h) inhibits h-cGAS in a

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) , with IC 50 s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activityIn VitroG140 (0.1-100 μM 4 h) inhibits h-cGAS in a

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) , with IC 50 s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activityIn VitroG140 (0.1-100 μM 4 h) inhibits h-cGAS in a

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) , with IC 50 s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activityIn VitroG140 (0.1-100 μM 4 h) inhibits h-cGAS in a

GLPG2534 is an orally active and selective IRAK4 inhibitor, with IC 50 values of 6.4 nM and 3.5 nM for human and mouse IRAK4 . GLPG2534 can be used for the research of inflammatory skin diseasesIn VitroGLPG2534 (2 h) inhibits IRAK4 with IC 50 values

GLPG2534 is an orally active and selective IRAK4 inhibitor, with IC 50 values of 6.4 nM and 3.5 nM for human and mouse IRAK4 . GLPG2534 can be used for the research of inflammatory skin diseasesIn VitroGLPG2534 (2 h) inhibits IRAK4 with IC 50 values

GLPG2534 is an orally active and selective IRAK4 inhibitor, with IC 50 values of 6.4 nM and 3.5 nM for human and mouse IRAK4 . GLPG2534 can be used for the research of inflammatory skin diseasesIn VitroGLPG2534 (2 h) inhibits IRAK4 with IC 50 values

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC 50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.In