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J648147-25mgJC2-11 is an inhibitor of inflammatory corpuscles. JC2-11 inhibits domain-containing protein NLRC 4 , absent in melanoma 2 ( AIM 2 ) and non-canonical ( NC ) inflammatory corpuscles. JC2-11 reduces the secretion of caspase-1 ( p20 ), the cleavage of
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J648147-50mgJC2-11 is an inhibitor of inflammatory corpuscles. JC2-11 inhibits domain-containing protein NLRC 4 , absent in melanoma 2 ( AIM 2 ) and non-canonical ( NC ) inflammatory corpuscles. JC2-11 reduces the secretion of caspase-1 ( p20 ), the cleavage of
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J648147-5mgJC2-11 is an inhibitor of inflammatory corpuscles. JC2-11 inhibits domain-containing protein NLRC 4 , absent in melanoma 2 ( AIM 2 ) and non-canonical ( NC ) inflammatory corpuscles. JC2-11 reduces the secretion of caspase-1 ( p20 ), the cleavage of
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J650941-10mgJH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in miceIn VitroJh-X-119-01 (10 μM) decreases phosphorylation of NF-κB and
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J650941-1mgJH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in miceIn VitroJh-X-119-01 (10 μM) decreases phosphorylation of NF-κB and
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J650941-50mgJH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in miceIn VitroJh-X-119-01 (10 μM) decreases phosphorylation of NF-κB and
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J650941-5mgJH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in miceIn VitroJh-X-119-01 (10 μM) decreases phosphorylation of NF-κB and
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J656471-1mlJH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in miceIn VitroJh-X-119-01 (10 μM) decreases phosphorylation of NF-κB and
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J647610-1mgJNJ-1013 is a potent and selective IRAK1 degrader with an IC 50 s of 72, 443, 1071 nM for IRAK1 , IRAK4 , VHL FP respectively. JNJ-1013 induces Apoptosis and increases the expression of cleavaged PARP . JNJ-1013 decreases the expression IRAK1 ,
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J647610-5mgJNJ-1013 is a potent and selective IRAK1 degrader with an IC 50 s of 72, 443, 1071 nM for IRAK1 , IRAK4 , VHL FP respectively. JNJ-1013 induces Apoptosis and increases the expression of cleavaged PARP . JNJ-1013 decreases the expression IRAK1 ,
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K650537-100mgK145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC 50 of 4.3 µM and a K i of 6.4 µM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis
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K650537-10mgK145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC 50 of 4.3 µM and a K i of 6.4 µM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis