Ligands of Immunopharmacology

KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5) , with an IC 50 of 0.1 μM.In VitroKRN2 selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6, without hampering

KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5) , with an IC 50 of 0.1 μM.In VitroKRN2 selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6, without hampering

KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5) , with an IC 50 of 0.1 μM.In VitroKRN2 selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6, without hampering

KRN5, a derivative of KRN2, is an oral active Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC 50 of 750 nM. KRN5 has potential to treat NFAT5-mediated Chronic ArthritisIn VitroKRN5 is less toxic than BBR as determined by a

KRN5, a derivative of KRN2, is an oral active Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC 50 of 750 nM. KRN5 has potential to treat NFAT5-mediated Chronic ArthritisIn VitroKRN5 is less toxic than BBR as determined by a

KRN5, a derivative of KRN2, is an oral active Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC 50 of 750 nM. KRN5 has potential to treat NFAT5-mediated Chronic ArthritisIn VitroKRN5 is less toxic than BBR as determined by a

KRN5, a derivative of KRN2, is an oral active Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC 50 of 750 nM. KRN5 has potential to treat NFAT5-mediated Chronic ArthritisIn VitroKRN5 is less toxic than BBR as determined by a

KRN5, a derivative of KRN2, is an oral active Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC 50 of 750 nM. KRN5 has potential to treat NFAT5-mediated Chronic ArthritisIn VitroKRN5 is less toxic than BBR as determined by a

KRN5, a derivative of KRN2, is an oral active Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC 50 of 750 nM. KRN5 has potential to treat NFAT5-mediated Chronic ArthritisIn VitroKRN5 is less toxic than BBR as determined by a

Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree ( Morus alba L.) inhibits nitric oxide production with an IC 50 of 10.5 μM.In VitroKuwanon A shows significant inhibitory activity towards the differentiation of

Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree ( Morus alba L.) inhibits nitric oxide production with an IC 50 of 10.5 μM.In VitroKuwanon A shows significant inhibitory activity towards the differentiation of

KYN-101 is a potent, selective and orally active AHR inhibitor. KYN-101 decreases the CYP1A1 mRNA expression. KYN-101 shows anti-cancer activity.In VitroKYN-101 (0.5, 1 µM 24 h) decreases the CYP1A1 mRNA expression in IDO high samples. MCE has not