Ligands of Immunopharmacology

PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC 50 of 115 nM. PD-L1-IN-1 strongly binds with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells

PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC 50 of 115 nM. PD-L1-IN-1 strongly binds with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells

PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC 50 of 115 nM. PD-L1-IN-1 strongly binds with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells

PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC 50 of 115 nM. PD-L1-IN-1 strongly binds with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells

PD1-PDL1-IN 1 TFA (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 TFA is useful as immune modulator.Appearance:SolidIn Vitro:PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is

PD1-PDL1-IN 1 TFA (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 TFA is useful as immune modulator.Appearance:SolidIn Vitro:PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is

PD1-PDL1-IN 1 TFA (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 TFA is useful as immune modulator.Appearance:SolidIn Vitro:PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is

Pepinh-TRIF (TFA) is a 30 aa peptide that blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction.Appearance:SolidIC50&amp Target:TLRsIn Vitro:Pepinh-TRIF (40 μM, 6 hours) blocks the

Pepinh-TRIF (TFA) is a 30 aa peptide that blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction.Appearance:SolidIC50&amp Target:TLRsIn Vitro:Pepinh-TRIF (40 μM, 6 hours) blocks the

Pepinh-TRIF (TFA) is a 30 aa peptide that blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction.Appearance:SolidIC50&amp Target:TLRsIn Vitro:Pepinh-TRIF (40 μM, 6 hours) blocks the

PF-06426779 is a potent and selective inhibitor of interleukin‑1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nMIn VitroPF-06426779 inhibits IRAK4, with an IC 50 of 12.7 nM in the peripheral blood mononuclear cells (PBMCs) assay. MCE

PF-06426779 is a potent and selective inhibitor of interleukin‑1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nMIn VitroPF-06426779 inhibits IRAK4, with an IC 50 of 12.7 nM in the peripheral blood mononuclear cells (PBMCs) assay. MCE