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A655652-1mlAZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM) AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma .In VitroThe affinity of AZD5423 to the
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B649790-1mgBI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC 50 value of 55 nM. BI 653048 inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel ( IC 50
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B129286-100gBufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.A HDAC6 and HDAC10 inhibitor.
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B129286-1gBufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.A HDAC6 and HDAC10 inhibitor.
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B129286-25gBufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.A HDAC6 and HDAC10 inhibitor.
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B129286-5gBufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.A HDAC6 and HDAC10 inhibitor.
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D649407-10mgDazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor ( GR ) modulator with a K i value In VitroIn HepG2 human cells or in human hepatocytes, Dazucorilant acts as full antagonist since it is able to prevent
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D649407-5mgDazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor ( GR ) modulator with a K i value In VitroIn HepG2 human cells or in human hepatocytes, Dazucorilant acts as full antagonist since it is able to prevent
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D155733-100gDiclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Target: COX Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing
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D155733-1gDiclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Target: COX Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing
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D155733-25gDiclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Target: COX Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing
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D155733-500gDiclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Target: COX Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing