PROTACs, molecular glues and other degraders

inhibitors of Mcl-1.

inhibitors of Mcl-1.

inhibitors of Mcl-1.

inhibitors of Mcl-1.

inhibitors of Mcl-1.

Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.Appearance:OilIC50&amp: Target:CereblonIn Vitro:PROTACs contain two different

Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.Appearance:OilIC50&amp: Target:CereblonIn Vitro:PROTACs contain two different

GNE-987 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 . GNE-987 exhibits picomolar cell BRD4 degradation activity ( DC 50 =0.03 nM for EOL-1 AML cell line). GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with

GNE-987 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 . GNE-987 exhibits picomolar cell BRD4 degradation activity ( DC 50 =0.03 nM for EOL-1 AML cell line). GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with

GNE-987 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 . GNE-987 exhibits picomolar cell BRD4 degradation activity ( DC 50 =0.03 nM for EOL-1 AML cell line). GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with

HO-PEG-CH2COOH (MW 10000) is a PEG polymer with -COOH that can be used as a PROTAC linker to the synthesis of PROTACs.Appearance:SolidBiological Activity:HO-PEG-CH2COOH (MW 10000) is a PEG polymer with -COOH that can be used as a PROTAC linker to

HO-PEG-CH2COOH (MW 10000) is a PEG polymer with -COOH that can be used as a PROTAC linker to the synthesis of PROTACs.Appearance:SolidBiological Activity:HO-PEG-CH2COOH (MW 10000) is a PEG polymer with -COOH that can be used as a PROTAC linker to