PROTACs, molecular glues and other degraders

Iodo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Appearance:LiquidIC50&amp: Target:PEGsIn Vitro:PROTACs contain two different ligands connected by a linker: one is a ligand for an E3 ubiquitin ligase and

Iodo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Appearance:LiquidIC50&amp: Target:PEGsIn Vitro:PROTACs contain two different ligands connected by a linker: one is a ligand for an E3 ubiquitin ligase and

Iodo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Appearance:LiquidIC50&amp: Target:PEGsIn Vitro:PROTACs contain two different ligands connected by a linker: one is a ligand for an E3 ubiquitin ligase and

JH-XI-10-02.

JH-XI-10-02.

KTX-951 is a PROTAC targeting IRAK4 degradation ( DC 50 =18 nM). KTX-951 (10 mg/kg) shows the oral bioavailability (F%) of 22% in a rat model. KTX-951 has good anticancer potentialForm:SolidIC50&amp: Target:IRAK4.

Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC

Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC

Lenalidomide-C5-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs , such as MDM2 PROTAC

Lenalidomide-C5-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs , such as MDM2 PROTAC

Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs , such as MDM2 PROTAC

Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs , such as MDM2 PROTAC