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M650560-5mgMS177 is an effective and fast-acting EZH2 degrader. MS177 is a PROTAC that consists of a CRBN ligand, linker, and a potent enzymatic EZH2 inhibitor C24 (C24 IC 50 ): 12 nM). MS177 effectively depletes both canonical EZH2–PRC2 and noncanonical
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M656316-1mlMS177 is an effective and fast-acting EZH2 degrader. MS177 is a PROTAC that consists of a CRBN ligand, linker, and a potent enzymatic EZH2 inhibitor C24 (C24 IC 50 ): 12 nM). MS177 effectively depletes both canonical EZH2–PRC2 and noncanonical
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M649194-10mgMTX-23 is an AR-based PROTAC. MTX-23 inhibits CaP cellular proliferation by degrading AR-V7 and AR-FL. MTX-23 induces apoptosis.In VitroMTX-23 (compound 16: 0-20 μM: 4 d: 22Rvl cells) inhibits cell growth in dose-dependent manner. MTX-23 (10 μM: 4
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M649194-1mgMTX-23 is an AR-based PROTAC. MTX-23 inhibits CaP cellular proliferation by degrading AR-V7 and AR-FL. MTX-23 induces apoptosis.In VitroMTX-23 (compound 16: 0-20 μM: 4 d: 22Rvl cells) inhibits cell growth in dose-dependent manner. MTX-23 (10 μM: 4