PROTACs, molecular glues and other degraders

PROTAC EED degrader-1 is a von Hippel-Lindau -based PROTAC targeting EED with a pK D of 9.02. PROTAC EED degrader-1 is a polycomb repressive complex 2 ( PRC2 ) inhibitor ( pIC 50 =8.17) targeting the EED subunitIn VitroPROTAC EED degrader-1

PROTAC EED degrader-2 is a von Hippel-Lindau -based PROTAC targeting EED with a pK D of 9.27. PROTAC EED degrader-2 is a polycomb repressive complex 2 ( PRC2 ) inhibitor ( pIC 50 =8.11) targeting the EED subunitIn VitroPROTAC EED degrader-2

PROTAC EED degrader-2 is a von Hippel-Lindau -based PROTAC targeting EED with a pK D of 9.27. PROTAC EED degrader-2 is a polycomb repressive complex 2 ( PRC2 ) inhibitor ( pIC 50 =8.11) targeting the EED subunitIn VitroPROTAC EED degrader-2

PROTAC EED degrader-2 is a von Hippel-Lindau -based PROTAC targeting EED with a pK D of 9.27. PROTAC EED degrader-2 is a polycomb repressive complex 2 ( PRC2 ) inhibitor ( pIC 50 =8.11) targeting the EED subunitIn VitroPROTAC EED degrader-2

PROTAC ER Degrader-4 is a von Hippel-Lindau -based PROATC estrogen receptor ( ER ) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC 50 of 0.3 nMIn VitroPROTAC ER Degrader-4 shows

PROTAC ER Degrader-4 is a von Hippel-Lindau -based PROATC estrogen receptor ( ER ) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC 50 of 0.3 nMIn VitroPROTAC ER Degrader-4 shows

PROTAC ERRα Degrader-3 is a potent and selective ERRα degrader based on von Hippel-Lindau ligand. PROTAC ERRα Degrader-3 is capable of specifically degrading ERRα protein by &gt:80% at a concentration of 30 nM. PROTAC ERRα Degrader-3 is inactive

PROTAC ERRα Degrader-3 is a potent and selective ERRα degrader based on von Hippel-Lindau ligand. PROTAC ERRα Degrader-3 is capable of specifically degrading ERRα protein by &gt:80% at a concentration of 30 nM. PROTAC ERRα Degrader-3 is inactive

PROTAC ERRα Degrader-3 is a potent and selective ERRα degrader based on von Hippel-Lindau ligand. PROTAC ERRα Degrader-3 is capable of specifically degrading ERRα protein by &gt:80% at a concentration of 30 nM. PROTAC ERRα Degrader-3 is inactive

PROTAC ERRα Degrader-3 is a potent and selective ERRα degrader based on von Hippel-Lindau ligand. PROTAC ERRα Degrader-3 is capable of specifically degrading ERRα protein by &gt:80% at a concentration of 30 nM. PROTAC ERRα Degrader-3 is inactive

PROTAC ERRα Degrader-3 is a potent and selective ERRα degrader based on von Hippel-Lindau ligand. PROTAC ERRα Degrader-3 is capable of specifically degrading ERRα protein by &gt:80% at a concentration of 30 nM. PROTAC ERRα Degrader-3 is inactive

PROTAC ERα Degrader-1 comprises an ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Degrader-1 extracts from patent WO2017201449A1, compound P1. PROTAC ERα Degrader-1 is an estrogen receptor-alpha ( ERα )