SARS-CoV-2 Inhibitors

Potent NS3/4A protease inhibitor.

Potent NS3/4A protease inhibitor.

Potent NS3/4A protease inhibitor.

InformationDanoprevir (ITMN-191, RG7227) is a peptidomimetic inhibitor of theNS3/4A proteaseof hepatitis C virus (HCV) withIC50of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.In vitroDanoprevir

InformationDaunorubicin HCl (Daunomycin, RP 13057, Rubidomycin) inhibits both DNA and RNA synthesis and inhibitsDNAsynthesis withKiof 0.02 μM in a cell-free assay. Daunorubicin is atopoisomerase IIinhibitor that inducesapoptosis.In vitroAt drug

Hydroxychloroquine sulfate.

Indinavir sulfate.

Indinavir sulfate.

Indinavir sulfate.

Indinavir sulfate.

InformationIvermectin (MK-933, IVM) is a glutamate-gatedchloride channel(GluCls) activator, used as a broad-spectrum antiparasitic drug. Ivermectin (MK-933, IVM) is a specific positive allosteric effector ofP2X4andα7 nicotinic acetylcholine

InformationLamivudine (BCH-189, GR109714X) is a potent nucleoside analogreverse transcriptaseinhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking theHIV reverse transcriptaseandhepatitis B virus