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P129617-1gPitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting
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P129617-250mgPitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting
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P129617-50mgPitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting
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P421721-1mlPitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting
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P408130-1mlInformationPraziquantel is an anthelmintic effective against flatworms.In vitroIn vivoCell Datacell lines:androgen-sensitive Shionogi cellConcentrations:Incubation Time:Powder Purity:≥99%.
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R408405-1mlInformationRemdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrumantiviralagent with in vitro activity against multiple RNA viruses, including Ebola and CoV.In vitroGS-5734 exhibits antiviral
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R408427-1mlInformationRitonavir (ABT-538, A 84538, RTV, Norvir, Norvir Softgel) is aCytochrome P450 3AandProteaseInhibitor: Also inhibitsCytochrome P450 2D6,P-Glycoproteinand inducesCytochrome P450 2C19,Cytochrome P450 1A2,Cytochrome P450 2C9,Cytochrome P450
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R408257-1mlInformationRosuvastatin Calcium (ZD4522) is a competitive inhibitor ofHMG-CoA reductasewithIC50of 11 nM in a cell-free assay.In vitroRosuvastatin is relatively hydrophilic and is highly selective for hepatic cells: its uptake is mediated by the
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T409003-1mlInformationTDZD-8 (NP 01139) is a non-ATP competitiveGSK-3βinhibitor withIC50of 2 μM: minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.In vitroTDZD-8 acts as a noncompetitive inhibitor of ATP or GS-1 binding. TDZD-8 shows no
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T409276-1mlInformationTenofovir (GS-1278) blocksreverse transcriptaseand hepatitis B virus infections.In vitroTenofovir reduces the viral cytopathic effect of HIV-1(IIIB), HIV-2(ROD) and HIV(EHO) with EC50 of 1.15 μg/mL, 1.12 μg/mL and 1.05 μg/mL in MT-4