Synthetic organic

aficamten.

aficamten.

aficamten.

AFP-07.

AFP-07.

InformationAfuresertib (GSK2110183) is a potent, orally bioavailableAktinhibitor withKiof 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.TargetsAkt1 (Cell-free assay): Akt2 (Cell-free assay): Akt3 (Cell-free assay) 0.08

InformationAfuresertib (GSK2110183) is a potent, orally bioavailableAktinhibitor withKiof 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.TargetsAkt1 (Cell-free assay): Akt2 (Cell-free assay): Akt3 (Cell-free assay) 0.08

InformationAfuresertib (GSK2110183) is a potent, orally bioavailableAktinhibitor withKiof 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.TargetsAkt1 (Cell-free assay): Akt2 (Cell-free assay): Akt3 (Cell-free assay) 0.08

Selective GnRH receptor antagonist.

Selective GnRH receptor antagonist.

Selective GnRH receptor antagonist.

Selective GnRH receptor antagonist.