Synthetic organic

AMG28.

AMG28.

InformationAMG319 is a potent and selectivePI3Kδinhibitor withIC50of 18 nM, &gt:47-fold selectivity over other PI3Ks. Phase 2.TargetsPI3Kδ : PI3Kγ 18 nM: 850 nMIn vitroAMG319 inhibits anti-IgM/CD40L-induced B cell proliferation with IC50 of 8.6 nM

InformationAMG319 is a potent and selectivePI3Kδinhibitor withIC50of 18 nM, &gt:47-fold selectivity over other PI3Ks. Phase 2.TargetsPI3Kδ : PI3Kγ 18 nM: 850 nMIn vitroAMG319 inhibits anti-IgM/CD40L-induced B cell proliferation with IC50 of 8.6 nM

InformationAMG319 is a potent and selectivePI3Kδinhibitor withIC50of 18 nM, &gt:47-fold selectivity over other PI3Ks. Phase 2.TargetsPI3Kδ : PI3Kγ 18 nM: 850 nMIn vitroAMG319 inhibits anti-IgM/CD40L-induced B cell proliferation with IC50 of 8.6 nM

InformationAMG319 is a potent and selectivePI3Kδinhibitor withIC50of 18 nM, &gt:47-fold selectivity over other PI3Ks. Phase 2.TargetsPI3Kδ : PI3Kγ 18 nM: 850 nMIn vitroAMG319 inhibits anti-IgM/CD40L-induced B cell proliferation with IC50 of 8.6 nM

InformationAMG319 is a potent and selectivePI3Kδinhibitor withIC50of 18 nM, &gt:47-fold selectivity over other PI3Ks. Phase 2.TargetsPI3Kδ : PI3Kγ 18 nM: 850 nMIn vitroAMG319 inhibits anti-IgM/CD40L-induced B cell proliferation with IC50 of 8.6 nM

AMG628.

AMG628.

AMG650.

AMG650.

AMG7703.