Synthetic organic

Potent, selective γ-secretase inhibitor.

Potent, selective γ-secretase inhibitor.

Potent, selective γ-secretase inhibitor.

Potent, selective γ-secretase inhibitor.

Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, &gt:121-fold selectivity over other PDEs.

Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, &gt:121-fold selectivity over other PDEs.

Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, &gt:121-fold selectivity over other PDEs.

Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, &gt:121-fold selectivity over other PDEs.

Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, &gt:121-fold selectivity over other PDEs.

InformationAvapritinib (BLU-285) is a small molecule kinase inhibitor that potently inhibitsPDGFRα D842Vmutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM): also a potent inhibitor of

InformationAvapritinib (BLU-285) is a small molecule kinase inhibitor that potently inhibitsPDGFRα D842Vmutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM): also a potent inhibitor of

InformationAvapritinib (BLU-285) is a small molecule kinase inhibitor that potently inhibitsPDGFRα D842Vmutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM): also a potent inhibitor of