Synthetic organic

InformationAZD7325 is a positive allosteric modulator (PAM) of α2,3 subtype-selective GABA receptor with pKi of 9.51 and has less efficacy at the α1 and α5 receptor subtypes. AZD7325 is a moderate CYP1A2 and a potent CYP3A4 inducer in vitro.

InformationAZD7325 is a positive allosteric modulator (PAM) of α2,3 subtype-selective GABA receptor with pKi of 9.51 and has less efficacy at the α1 and α5 receptor subtypes. AZD7325 is a moderate CYP1A2 and a potent CYP3A4 inducer in vitro.

InformationAZD7325 is a positive allosteric modulator (PAM) of α2,3 subtype-selective GABA receptor with pKi of 9.51 and has less efficacy at the α1 and α5 receptor subtypes. AZD7325 is a moderate CYP1A2 and a potent CYP3A4 inducer in vitro.

InformationAZD7325 is a positive allosteric modulator (PAM) of α2,3 subtype-selective GABA receptor with pKi of 9.51 and has less efficacy at the α1 and α5 receptor subtypes. AZD7325 is a moderate CYP1A2 and a potent CYP3A4 inducer in vitro.

InformationAZD7325 is a positive allosteric modulator (PAM) of α2,3 subtype-selective GABA receptor with pKi of 9.51 and has less efficacy at the α1 and α5 receptor subtypes. AZD7325 is a moderate CYP1A2 and a potent CYP3A4 inducer in vitro.

azd-8186.

azd-8186.

azd-8186.

azd-8186.

InformationAZD0156 is a potent and selective inhibitors ofATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities. AZD0156 prevents DNA damage checkpoint activation, disrupts DNA damage repair, induces tumor cell apoptosis,

InformationAZD0156 is a potent and selective inhibitors ofATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities. AZD0156 prevents DNA damage checkpoint activation, disrupts DNA damage repair, induces tumor cell apoptosis,

InformationAZD0156 is a potent and selective inhibitors ofATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities. AZD0156 prevents DNA damage checkpoint activation, disrupts DNA damage repair, induces tumor cell apoptosis,