Synthetic organic

AZD2014 is a novel mTOR inhibitor with IC50 of 2.8 nM: highly selective against multiple PI3K isoforms (α/β/γ/δ).A selective inhibitor of mTOR kinase.

AZD2014 is a novel mTOR inhibitor with IC50 of 2.8 nM: highly selective against multiple PI3K isoforms (α/β/γ/δ).A selective inhibitor of mTOR kinase.

AZD2423.

AZD2423.

AZD2461 is a novel PARP inhibitor, which has the potential to avoid the olaparib resistence mediated by Pgp.

AZD2461 is a novel PARP inhibitor, which has the potential to avoid the olaparib resistence mediated by Pgp.

AZD2461 is a novel PARP inhibitor, which has the potential to avoid the olaparib resistence mediated by Pgp.

AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, inhibits tau phosphorylation at the S396 site, activates Wnt signaling pathway.

AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, inhibits tau phosphorylation at the S396 site, activates Wnt signaling pathway.

AZD2906.

AZD2906.

AZD2927.